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Have you ever see a good trade, your indicators say to get in, and you just cannot ‘pull the trigger’

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

for some reason?

The trade signal has been given, your trading system have been determined, and all

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

that is left to do is make the phone call to your broker, or hit 'enter' button on your computer keyb

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

oard. But at this point, all the doubt and second-guessing comes to a head, and the trade never gets

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

laced. Sound familiar? It is probably the most common heartache faced by many traders, and is only co

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

mpounded when it turns out to be a great trade. That a tough issue and there is really no magical ans

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

er to get past it.

Firstly, your system has found a trading opportunity that fits your criteria. The

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

next step is to actually place the trade. As all of you know, this is much easier said than done. Su

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

denly you become very good at second guessing, and you find a few dozen reasons not to enter the trad

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

e after all. Here are some of the things you might have said to yourself: “My main signal says one th

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ng, but all the other indicators say something else” or “What if I am wrong?” These are tough things

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

o deal with. Uncertainty and regret are powerful emotions that can weaken even the best of traders. T

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

here are some things you have to remember if you get to this point: First of all, at no point in time

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

will all signals be in agreement. That is just the nature of technical analysis. Sometimes the obviou

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

s or logical trade is not always the profitable trade. Sometimes the market is transparent, and somet

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

mes its true nature is completely hidden. And of course you are going to occasionally be wrong, so ge

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

t used to that. Even your tested and proven trading system will not be perfectly accurate. As for the

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

consequences of being wrong, that is what stops are for.

So when in doubt, perhaps the best thing to

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

do is to review your strategy on stops. If you can be reassured that even if the trade goes bad you

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ill lose a minimal amount of money, it should help get that confidence to go ahead and make the trade

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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You’re psyched! You just landed a new client who is going to keep you busy with projects. Life is good. You love the people, you’re really enjoying the work, things are going great. Everything proceeds along smoothly for several months until that fateful month where you submit a large invoice and payment isn’t immediate. “No problem” you think. “Things are somewhat tight. It will just be paid a little late.” What are your options when a client doesn’t – or can’t – pay you?

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