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Most countries have a stock-exchange where you can trade the stocks of the various companies. If you are starting the

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

investment game, the stock market just looks like a raw list of data (The list below represents the IBEX 35 which is t

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

e stock index of the Stock-Exchange of Madrid (source: www.bolsamadrid.es/esp/mercados/acciones):

ABERTIS SE.A
A

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

CIONA ACERINOX
ACS ALTADIS
ANTENA 3 TV.
ARCELOR
BA.POPULAR
BA.SABADELL
BANKINTER
BB

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

A
BSCH
CINTRA
ENAGAS
ENDESA
FCC
FERROVIAL
GAMESA
GAS NATURAL
IBERDROLA

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

> IBERIA
INDITEX
INDRA A
METROVACESA
NH HOTELES
PRISA
R.E.E.
REPSOL YPF
SACYR

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

VALLE.
SOGECABLE
TELECINCO
TELEFONICA
TELF.MOVILES
TPI
UNION FENOSA

If you take a close

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

look by adding some company information for each stock you could present the same list but sorted in a different way

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

sing (sector) categories. Which could look like the list below:

Companies in the area of infrastructure and communica

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

tion:

ABERTIS SE.A
CINTRA
TELEFONICA
TELF.MOVILES

Constructi

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

n and real estate sector:

FCC
FERROVIAL
METROVACESA
SACYR VALLE.

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

Companies in the area of commodities (Steel)

ACCIONA ACERINOX
ARCELOR

Tobacco industry

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ACS ALTADIS

Entertainment, broadcasting (information distribution):

ANTENA 3 TV.

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

PRISA (amongst others the newspaper El Pais)

SOGECABLE

TELECINCO

TPI

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

Financial services

BA.POPULAR
BA.SABADELL
BANKINTER
BBVA
BSCH
t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
i>

Energy sector:

ENAGAS
ENDESA
GAS NATURAL
IBERDROLA
R.E.E

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

REPSOL YPF

UNION FENOSA

Transport and distribution:

IBERIA
INDI

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

TEX (Fashion, Textile)

(Industrial) Production:

GAMESA (Wind Turbines)
INDRA A (Softwa

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

e Development)

Business services – Hotel sector:

NH HOTELES

Now that you have this li

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

t you can start the investment process; what sector(s) do I choose, and what stock would be the best for each sector..

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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As business owners, we have a responsibility to pay our debts. Whether it's paying our bills, finalizing payment for a service provided, or paying our employees we are the ones who are accountable to ensure that all business expenses get paid in a timely manner.

To avoid blunders, companies wishing to internationalize their business should use locally based translators and agencies in the destination countries. This article refers to services that can be useful for those companies that are not sure of the differences between translating and localizing.

Before starting any search engine optimization campaign it is crucial to target the right set of keyword phrases for your market. Often times the most obvious keywords aren’t always the best. This can be the case for a number of reasons. When choosing the right keyword phrases, it is important to remember three elements: popularity, competition, and relevance.

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