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The 188 stage Hero's Journey (Monomyth) is the template upon which the vast majority of successful stories and Hollywood blockb

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

usters are based upon. In fact, ALL of the hundreds of Hollywood movies we have deconstructed (see URL below) are based on this 188+ sta

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

e template.

Understanding this template is a priority for story or screenwriters. This is the template you must master if you are to su

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

cceed in the craft.

[The terminology is most often metaphoric and applies to all successful stories and screenplays, from The Godfather

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

(1972) to Brokeback Mountain (2006) to Annie Hall (1977) to Lord of the Rings (2003) to Drugstore Cowboy (1989) to Thelma and Louise (19

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

1) to Apocaplyse Now (1979)].

THERE IS ONLY ONE STORY

THE 188 STAGE HERO'S JOURNEY:

a) Attempts to tap into unconscious expectations

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

the audience has regarding what a story is and how it should be told.

b) Gives the writer more structural elements than simply three or

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

four acts, plot points, mid point and so on.

c) Gives you a tangible process for building and releasing dissonance (establishing and ac

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ieving catharses, of which there are usually four).

d) Tells you what to write. For example, at a certain stage of the story, the focus

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

should be on the Call to Adventure and the micro elements within.

ABRIDGED TIPS, EXCERPTS AND EXAMPLES:

(simply go to ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

href="http://www.story-structure.org/">http://www.story-structure.org/ for full details)

*****Rebellion*****

It not uncommon for

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

he Hero to embark on the Journey or Trivial Task through a minor act of rebellion. The Hero takes the initiative. In The Incredibles (20

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

04), Mr Incredible rebels and deceives his wife. In An Officer and a Gentleman (1982), Zach rebels against his father.

*****Call to Adv

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

nture*****

A staple of the Hero's Journey and Transformation. Separate and distinct from the Inciting Incident. A Call for the Hero to

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

et out on a Journey; an implicit Call to face Challenges. It is the undergoing of the Journey that will Transform the Hero and provide h

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

im (or her) with the capacity to conquer challenges that were previously unconquerable. In Bonnie and Clyde (1967), Clyde invites Bonnie

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

for a drink.

*****Marker of Change*****

Change is in the air and it is illustrated by a marker (before embarking on the Road of Trials

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

. In Dances with Wolves (1990), the buffalo arrive. In Godfather (1972), the exchange of gifts and the chaperones foreshadow a new begin

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ning. In Romancing the Stone (1984), Joan looks at Jack with bedroom eyes.

*****Magical Gifts*****

Magical Gifts (often given by a Men

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

or or Supernatural Aid) do not have to be Harry Potter's Wand or Ruby Slippers. In Brokeback Mountain (2005), it is simply a set of guns

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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