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The Hero's Journey (Monomyth) is the template upon which the vast majority of successful stories and Hollywood blockbusters are based upon. In

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

fact, ALL of the hundreds of Hollywood movies we have deconstructed (see URL below) are based on this 188+ stage template.

Understanding this

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

template is a priority for story or screenwriters. This is the template you must master if you are to succeed in the craft.

[The terminology i

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

s most often metaphoric and applies to all successful stories and screenplays, from The Godfather (1972) to Brokeback Mountain (2006) to Annie

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

Hall (1977) to Lord of the Rings (2003) to Drugstore Cowboy (1989) to Thelma and Louise (1991) to Apocaplyse Now (1979)].

THERE IS ONLY ONE ST

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

RY

THE HERO'S JOURNEY:

a) Attempts to tap into unconscious expectations the audience has regarding what a story is and how it should be told.

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

b) Gives the writer more structural elements than simply three or four acts, plot points, mid point and so on.

c) Gives you a tangible proce

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

ss for building and releasing dissonance (establishing and achieving catharses, of which there are usually four).

d) Gives you a universal str

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

uctural template upon which you can superimpose your situational story. This is why stories such as Alien (1979), Gladiator (2000), Midnight Co

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

wboy (1969), American Beauty (1999), The Graduate (1967) and many others (all deconstructed at the URL below) appear to be different but are al

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

constructed, almost sequence by sequence, in the same way.

and more...

ABRIDGED TIP(S):

*****Communion*****

Unresolved issues are resolved

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

, that is, the regression is resolved (post Trial 3 and the conquest of the Outer Challenge). In Transamerica (2005), Toby leads Bree to Sammy'

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

s Wigwam.

Water. The Communion is often held in a place where water is abundant, a pool, sauna, bog or similar. Water is representative of cle

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

anliness, wiping away the Old Self and Renewal. In Transamerica (2005), Toby tells Bree that she's not a freak, just a liar, in the pool.

****

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

*The Four Core Challenge categories can be viewed as classes*****

Hero's often have to resolve Four Core Challenges: the Inner, Outer, Romanti

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

and Greater Antagonism. Each Challenge is made explicit and resolved in a very specific order. Each Core Challenge can be viewed as a class.

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

In Tootsie (Academy Award Nominee Best Film 1982), Michael's Romantic Challenge is Julie, his Inner Challenge is represented by his penultimate

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

line "I was a better man with you as a woman than I ever was with a woman as a man...I just gotta learn to do it without the dress...", his Ou

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ter Challenge is Ron [symbol of male condescension] and the Greater Antagonism is his problem that the network and fans thinks he's really a wo

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

man. But within the class of the Inner Challenge is Sandy and within the class of the Romantic Challenge are the attentions of Les and Van Horn

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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