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One of the most common blunders by those using article marketing to distribute free reprint articles is to include periods after domain names at the end of sentences. Surely those authors who have made this blunder realize that if that period gets included in the URL, the link will lead to a 404 er

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

ror or "Page Not Found" message any time a visitor clicks on your link from any web site that used your articles. Publishers complicate things by not visiting links included in author resource boxes and failing to correct the address error in the URL once they do notice it.

To be fair to publishers

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

, it is often difficult to edit within some content management systems and it simply takes too much time to make those changes. To be fair to article authors, we certainly ought to be able to use correct punctuation in our writing, even if it does cause problems with automated link creation in CMS

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

(Content Management System) tools. To be fair to CMS programmers, writing exceptions into the software on CMS sytsems to remove that period leads to incomplete and truncated filenames along with other complex unintended consequences.

But the ultimate responsibility for this issue rests squarely on

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

the head of web content authors who write articles intended to gain them links from other websites. Most have figured out the eccentricities of the web and know how to avoid this problem after seeing a few bad links or URL's that are not hyperlinked by web content publishers. You MUST understand t

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

ese issues to successfully use article marketing to get your web content used by publishers.

For those web content authors who have NOT figured out the eccentricities of publishing on the web, here a a few guidelines:

1) I'll repeat the opening admonition here because it bears repeating as the mos

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

t common error by article marketers - Don't follow web addresses with periods or the resulting link will lead to an error page. Include a space between domain names and periods if you must use a period following a web address. Content Management Systems (CMS) used by web content publishers will inc

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

lude that period in the hyperlink!

2) Never cut and paste from Microsoft Word documents or other proprietary word processing software, because most use non-ascii text which replaces common punctuation with code unique to their software to create punctuation marks such as hyphens, elipses, quote mar

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

ks, accents, exclamation marks, dashes and underscores. It is very irritating to read articles that include those odd looking foreign characters on web pages. Most publishers cannot, and the remaining publishers WILL not take the time to fix those strange characters in your text before publishing t

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

hem to a web page or pasting them into their plain text newsletter. So your article simply will not be used in most cases.

3) Start a new line each time you include a web address within the body of the article AND in your resource boxes, because email clients often "break" web addresses if they are

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

longer than 64 characters. Count the characters in any web address you use in articles or in your resource boxes because if theyare longer than 64 characters, many will wrap onto the following line of text, those content management systems (CMS) will then ALSO truncate your web address and send any

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

one who clicks that incomplete URL to a "404 error, Page Not Found." Use one of the recognized URL shortening and forwarding services to make the longer web addresses short. My favorite is http://www.shorl.com

4) Don't use proprietary software to paste your articles INTO before distributing to ezi

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

ne editors, article distribution and web content sites because that proprietary software converts both previous proprietary punctuation from word processing software and previously ascii text punctuation within your article to use IT'S own proprietary punctuation which shows up on web pages as biza

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

rre foreign and unrecognizable characters as it sends that article to web publishers. Again, leading to your article not being used by web content publishers.

5) Always remember to use the leading http:// portion of web addresses that you want converted into links by web content publishers because,

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

once again, their content management system (CMS) won't recognize it as a URL (web address) if that portion is missing from the domain name. Most will not take the extra time to add that required element to your address to cause their CMS to embed the hyperlink for them and almost nobody will retu

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

n to add the hyperlink if their CMS fails to do it for them - many don't know how to write the necessary HTML to embed links but would be required to add it if their CMS didn't do it for them initially - so they can't link to you if they want to.

6) Use only those article distribution sources that

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

embed hyperlinks in your resource boxes to distribute your articles. I've run across dozens of sites using my articles that referred me back to the articles distributor saying, "They don't provide the hyperlink from their site". If you do use an article distribution source that DOESN'T automaticall

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

y embed hyperlinks for users of your articles, learn how to embed them yourself during submission. Most web content publishers simply will not take the time to add it if they use those article distribution sources that don't provide it to them.

7) Never distribute articles with HTML already include

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

d to embed links as it will result in web content publishers NOT using the articles because their CMS then DOUBLE embeds hyperlinks- often breaking those links and leading to further error pages. Even if it the resulting hyperlink works properly, it makes reading difficult since you'll then see the

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

HTML code displayed in unicode characters on the page of some sites.

Learn the bugaboos of Web CMS and take advantage of the knowledge to out-perform your article marketing competitors who haven't yet learned how to manage Content Management Systems to their advantage.

Copyright © August 12, 200

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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