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Like other forums, most of the CCNA forums also follow the same user level structure - administrators (peop

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

le assigned the highest level of control, including setting permissions, banning users, creating user group

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

s or moderators, etc.), moderators (having the power to edit or delete posts and lock, unlock, move, delete

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

, and split topics in the forum that they moderate), and user-groups (each user can belong to several group

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

, and each group can be assigned individual access rights making it easy for administrators to set up sever

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

al users as moderators of a forum).

There are several CCNA (Cisco Certified Network Associate) Forums avai

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

lable on the Internet, where users can discuss how to prepare for the CCNA exam or get a list of recommende

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

d books. These forums are an ideal place to discuss topics like exam experience and questions, apart from p

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

sting one's own experiences and questions about the CCNA exams.

The questions posed in such forums with ni

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

che user groups and focused subjects could be very technical in nature or it could be one where the user se

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

eks guidance for avoiding exam fever. Besides, becoming a part of a large and active forum obviates one's n

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

eed to wait for replies after posting a query. Instead, just searching for keywords in the query in all the

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

posts in the forum may do the job. Since the entire group on the forum is focused on just one course, it is

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

quite likely that one will find some post in the forum that answers the query that has been posed.

On the

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

other hand, there could also be several replies to the post. However, these forums face the same issue as

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

all others - the accuracy of the content. One may find several answers to a query posted on a forum, but on

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

needs to be cautious and judge for oneself which replies are accurate. It helps to know some simple rules

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

such as writing a very specific and to-the-point subject line for a query in order to avoid ineffective res

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ponses.

Thus, while there is no guarantee of the accuracy of the content on such forums, given a bit of fl

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

air for finding out the accurate content, these forums do help the students in preparing for the CCNA exams

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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Objections are critically important in successful negotiations and taking into account all objections is ecological. That is, it takes into account varying components of the system. Negotiations often prove a failure after the fact because one or more of the parties does not express their objections to the proposed settlement. Then, after the negotiation is over, they start to feel shortchanged and don’t abide by the agreement.

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