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Cuba. This island is known everywhere in the world. Everybody knows such names as Fidel Castro and Che Guevara. Also Cuba is associated with Caribbean crisis, which had frightened both the U.S.A. and USSR. That’s all that common person k

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

nows about this land and nation famous for specific culture and interesting history (especially of the 20th century). Cuba has always been a region of American interests in the Caribbean Sea and its 45-year resistance against capitalism

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

(in fact – American politics) impresses everyone, even person hostile to Cuban regime. That’s why before having a closer look on the gains of Cuban revolution it’s important to give the general characteristics of Cuba in the politics of

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

the modern world. It’s important to explore the reasons of Cuban revolution as well in order to better understand it’s purposes and the results in economical and social sphere that were achieved by Castro’s government after the revolutio

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

n was over. In this question it’s also important to pay attention to the relations of Cuba with foreign countries and with the USA particularly. Cuban influence on worlds politics during the Cold War and nowadays is important and worth

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

aying attention to. Cuba is still one of the last Communist countries of the world.

The revolution of 1958 had a lot of problems to be solved by the main were social and economical. The situation of Cuba in 1950ies was not pretty much d

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ifferent from any of the Latin America states, but still the poverty level was huge. Cuba was totally dependent upon foreign capitals and was an agricultural supplier of the USA. Before answering the question about the changes in politic

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

l, economical and social sphere which were achieved after revolution it’s important to identify the main reasons which led to the revolution and which directed the future destiny of the country.

Many years have past, Communism had a gre

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

at success but it died after Soviet Union collapsed. Now China and Vietnam try to democratize and capitalize own economics. Only Cuba and North Korea are still devoted to Communism. But even there we can find some ideas of capitalism. Th

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

majority of Socialistic revolutions (older and younger that Cuban) are history already. Some scientists admit that Cuban revolution took place in the most complicated situation and practically had no chance to come true. But Cubans prov

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

ed their moral strength and they still succeed protecting the Revolution. Cuban revolution created the first Socialistic state in this part of Earth. Now I’ll try to find out why Cuban Revolution of 1958 was inevitable. Also it is very i

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

nteresting and worth studying that Cuba was not the most developed country of Latin America and many people explain the Revolution with Fidels charisma, Russian success and American miscalculations. As historian Jules Benjamin in his boo

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

“The United States and Cuba” wrote, United States and Cuba had always very uneasy relations.

Cuba had a very tragic history before the middle of the 20th century. Spanish and later – American influence was not good for this island nati

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

on. We cannot name American influence of that time democratic because United States and owners of different companies considered Cuba as a colony. This influenced future revolution a lot.

Let us analyze Cuban economics and American infl

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ence on this island country. The basic sphere of pre-Revolutionary Cuban economics, as all historians say including Marifeli Perez-Stable in the book “The Cuban Revolution”, was producing sugar for export to the United States. 25% of be

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

st lands, 36 big and well-equipped sugar plants belonged to United Fruit and other American corporations. They produced 42% of sugar. Another 58% were produceв by Cubans but were also controlled by Americans.

But sugar was not the

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

only sphere of American monopolies interests. They controlled 23% of industry, 90% of electrical and telephone infrastructure, 50% of railways. For example telephone and telegraph belonged to the filial of ATT. Electricity and lands in s

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ome provinces belonged to Cuban American Sugar Company. These two companies were connected through Morgan bank group and received support from Department of State and CIA.

National Cuban capitalists were associated with American capital

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

and had interests both in Cuba and Miami. Different American companies wished to have a filial on this island involving some part of Cuban capital. So, the whole infrastructure of the island, industry and other spheres of national econom

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

ics were leaded by the United States.

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tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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