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Beyond considering the ethical and legal implications of the US Government's demand for Google's search frequency data to fight pornography and other age-inappropriate materials,

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

the government seems to have a real cause for concern. Although Google doesn't release its search frequency data, other smaller search engines do.

It’s the job of Epiar Inc., an

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

dmonton-based company, to collect and analyse this data, providing market research on the relative demand for various products and services, brand equity studies, and search engin

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

marketing data. Epiar recently turned its attention to studying the problem of child pornography.

The basis of the study involved investigating the search frequencies of the top

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

11,932 searched phrases containing the word "nude" or "naked". The results showed that, mixed with a seemingly endless list of celebrities (topped by Britney Spears), there are li

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

terally millions of searches per year using phrases that clearly indicate people are looking for child pornography.

In a separate analysis of the co-occurring words within these

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

hrases, Epiar found that out of an estimated billion searches per year containing the words "nude" or "naked", over 19 million also used the words "preteen" or "pre-teen". Well ov

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

r 10 million searches per year included the words "child", "children" or "kids" and 80 million searches included the word "girls" or “boys”.

These results represent just the tip

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

f the iceberg. The phrases analysed did not include hundreds of other child pornographic searches that may not use the words naked or nude. For example, an offender may also enter

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

"child porn" or "preteen porn". By Epiar's estimate, there are well over 500 million searches per year related to child pornography conducted by somewhere between 5 and 15 millio

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

offenders worldwide.

This information is, in essence, some of what the US government is demanding from Google. With over a 35% market share in searches, it naturally has the cap

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

bility of providing the largest sample size of search frequency data.

The Bush administration had originally asked for two months' worth of search terms; the millions of phrases

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

sed in about 25 billion searches. After the case received worldwide attention, the Department of Justice reduced its request to 5,000 phrases. On March 14, U.S. District Judge Jam

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

es Ware’s comments suggested that he is inclined to force Google to provide the government with, if not all, at least something.

Unfortunately, even if the government does overco

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

e the legal barriers to obtaining this data, the data has little value in actually nabbing the offenders. Google and other search engines only know what is being searched. What th

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

y don’t know is who is doing the searching.

The government, though, has stated that it intends to use the data to support their allegation that pornography is an extremely preval

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

nt and unavoidable part of the Internet, which will help the DOJ resurrect the Child Online Protection Act. Known as COPA, the act was passed in 1998 to protect children from harm

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

ful sexual material on the Internet but was blocked by the courts.

In the same action, the Bush administration originally asked for the billions of web pages Google has indexed,

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

ut has since reduced that to requiring a random sample of about 50,000 sites. Rival search engines Microsoft, Yahoo, and AOL have already complied with the government’s demands.

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

or more information on Epiar Inc., internet market research, or the details of this study, call 780.428.5530 or visit www.epiar.com

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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