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    According to the European Vending Association (www.eva.be) the Consumers’ increasingly nomadic lifestyle is a great opportunity for the vending industry. They e
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    xpect this out-of-home market to develop significantly in the next decade. Recent years have been difficult for the vending manufacturers and operators. As we
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    ave seen – the manufacturing industry provides the majority of the demand for these machines, but this market is slowing down, because of a shift from blue-collar to
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    white-collar workforce, also means that the type, range and quality of products supplied must be adapted. (www.eva.be).

    Some development that are to be expected in
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    the near future are;
    • Machines that sell products with payment via mobile phones
    • Machines equipped with internet browsers
    • Order panels with ta
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    tile screens
  • Machines that talk, for the blind or visually impaired
  • More environmentally-friendly machines, that use refrigerants that are harmless
  • ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    for the environment, that make better use of environmentally-friendly materials, or recycled ones, that use less energy... (www.eva.be) Other trends could b
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    imagined that the control of the machines could be arranged on distance by using mobile information technology. The growth-rate of the production in the US, measured
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    ver ten years is moderate. An increase of about 70 percent over ten year is less than 5% growth per year. Difficult to tell is what the development of different produc
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    s and sectors have done in this period. But the numbers “hide” this information. The European Vending association provides numbers of machines sold per period. This in
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    ormation is not sales oriented, but production oriented, for example:

    In Spain there were sold 29,049 machines in 2001 up to 34,148 in 2004. And overall growth rate of
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    18 percent, and nearly due to the growth in 2004.

    The situation in the Netherlands shows a growth rate of 25% but this is due to the growth in 1999. The situation sta
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    ilized since then. For Europe as such, the growth is also moderate of a twelve percent over the years 2001 to 2004 and in that case, this increase took place in 2004.

    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    oogle Trends demonstrates that people search less for “vending-machines” since 2004 and the Search engine suggest to read the following headline: Sex Toy Vending Machin
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    s Popular In Britain (http://www.nbc4.tv/irresistible/7779805/detail.html - 7 mar 2006).

    That headline sheds some more light on the usage of these machines. It is not
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    only) that it facilitates a purchase at any moment in time. And it goes beyond the nomadic lifestyle. Also interesting to know is that South Africa is the Top region f
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    or vending machine searches. But although the trend line seems to decline slowly it is difficult to tell what really the trend is for vending machines. But it seems re
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    sonable that these machine are still dependent of industry developments and that there are shifts from one category (manufacturing and beverages) to others (specialties
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    and niche markets). Automatic teller machines, which could be seen as a family product dedicated to banking operations, have increased over the years and provided a mas
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    ive shift in consumer behavior. The question is what tendencies in society will make that vending machines will grow beyond normal demographic growth.

    © 2006 Hans Boo


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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